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ea0035p948 | Steroid metabolism and action | ECE2014

Changes in serum steroid concentrations in relation to fat distribution and insulin resistance in women with polycystic ovarian syndrome

Ibanichuka Jacqueline , Vincent Royce P , Ghataore Lea , Taylor Norman F , Millward Ann , Pinkney Jonathan H , Stenhouse Elizabeth

Background: Polycystic ovarian syndrome (PCOS) affects 5–10% of women of reproductive age. Hyperandrogenism and hyperinsulinaemia have been attributed to the pathophysiology of PCOS. The aim of this study is to evaluate the effect of fat distribution and insulin resistance on steroid metabolism in PCOS.Methods: The study recruited 20 PCOS and 20 matched controls. Fat distribution was assessed by waist circumference, skin fold measurements, and body ...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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